Synthesis of Spirocyclic Indolines by Interruption of the Bischler–Napieralski Reaction

The development of a versatile method for the synthesis of spirocyclic pyrrolidinoindolines is discussed. Treatment of N-acyltryptamines with trifluoromethanesulfonic anhydride–2-chloropyridine reagent combination affords highly persistent spiroindoleninium ions that are subject to intra- and interm...

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Bibliographic Details
Main Authors: Medley, Jonathan William, Movassaghi, Mohammad
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2015
Online Access:http://hdl.handle.net/1721.1/95519
https://orcid.org/0000-0003-3080-1063