Redox-Linked Changes to the Hydrogen-Bonding Network of Ribonucleotide Reductase β2

Ribonucleotide reductase (RNR) catalyzes conversion of nucleoside diphosphates (NDPs) to 2′-deoxynucleotides, a critical step in DNA replication and repair in all organisms. Class-Ia RNRs, found in aerobic bacteria and all eukaryotes, are a complex of two subunits: α2 and β2. The β2 subunit contains...

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Detalhes bibliográficos
Principais autores: Offenbacher, Adam R., Minnihan, Ellen Catherine, Stubbe, JoAnne, Barry, Bridgette A.
Outros Autores: Massachusetts Institute of Technology. Department of Biology
Formato: Artigo
Idioma:en_US
Publicado em: American Chemical Society (ACS) 2015
Acesso em linha:http://hdl.handle.net/1721.1/95666
https://orcid.org/0000-0001-8076-4489