Redox-Linked Changes to the Hydrogen-Bonding Network of Ribonucleotide Reductase β2
Ribonucleotide reductase (RNR) catalyzes conversion of nucleoside diphosphates (NDPs) to 2′-deoxynucleotides, a critical step in DNA replication and repair in all organisms. Class-Ia RNRs, found in aerobic bacteria and all eukaryotes, are a complex of two subunits: α2 and β2. The β2 subunit contains...
Main Authors: | Offenbacher, Adam R., Minnihan, Ellen Catherine, Stubbe, JoAnne, Barry, Bridgette A. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2015
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Online Access: | http://hdl.handle.net/1721.1/95666 https://orcid.org/0000-0001-8076-4489 |
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