Delivering Heparin-Binding Insulin-Like Growth Factor 1 with Self-Assembling Peptide Hydrogels

Heparin-binding insulin-like growth factor 1 (HB-IGF-1) is a fusion protein of IGF-1 with the HB domain of heparin-binding epidermal growth factor-like growth factor. A single dose of HB-IGF-1 has been shown to bind specifically to cartilage and to promote sustained upregulation of proteoglycan synt...

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Bibliographic Details
Main Authors: Miller, Rachel Elizabeth, Mroszczyk, Keri A., Lee, Richard T., Patwari, Parth, Grodzinsky, Alan J., Florine, Emily Marie, Liebesny, Paul Hancock
Other Authors: Lincoln Laboratory
Format: Article
Language:en_US
Published: Mary Ann Liebert, Inc. 2015
Online Access:http://hdl.handle.net/1721.1/95793
https://orcid.org/0000-0002-4942-3456
https://orcid.org/0000-0002-4121-8183
https://orcid.org/0000-0002-5770-838X