Threonine 149 Phosphorylation Enhances  ΔFosB Transcriptional Activity to Control Psychomotor Responses to Cocaine

Threonine 149 Phosphorylation Enhances  ΔFosB Transcriptional Activity to Control Psychomotor Responses to Cocaine

Stable changes in neuronal gene expression have been studied as mediators of addicted states. Of particular interest is the transcription factor ΔFosB, a truncated and stable FosB gene product whose expression in nucleus accumbens (NAc), a key reward region, is induced by chronic exposure to virtual...

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Detalhes bibliográficos
Principais autores: Neve, Rachael L., Cates, Hannah M., Thibault, Mackenzie, Pfau, Madeline, Heller, Elizabeth, Eagle, Andrew, Gajewski, Paula, Bagot, Rosemary, Colangelo, Christopher, Abbott, Thomas, Rudenko, Gabby, Nestler, Eric J., Robinson, Alfred J.
Outros Autores: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Formato: Artigo
Idioma:en_US
Publicado em: Society for Neuroscience 2015
Acesso em linha:http://hdl.handle.net/1721.1/95796
https://orcid.org/0000-0002-3854-5968

Internet

http://hdl.handle.net/1721.1/95796
https://orcid.org/0000-0002-3854-5968

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