Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems

Hepatitis B virus (HBV) chronically infects 400 million people worldwide and is a leading driver of end-stage liver disease and liver cancer. Research into the biology and treatment of HBV requires an in vitro cell-culture system that supports the infection of human hepatocytes, and accurately recap...

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Bibliographic Details
Main Authors: Schwartz, Robert E., Ramanan, Vyas, Shlomai, Amir, de Jong, Ype P., Bhatia, Sangeeta N., Rice, Charles M., Bhatia, Sangeeta N
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2015
Online Access:http://hdl.handle.net/1721.1/95798
https://orcid.org/0000-0001-6214-4788
https://orcid.org/0000-0002-1293-2097