Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
Hepatitis B virus (HBV) chronically infects 400 million people worldwide and is a leading driver of end-stage liver disease and liver cancer. Research into the biology and treatment of HBV requires an in vitro cell-culture system that supports the infection of human hepatocytes, and accurately recap...
Main Authors: | , , , , , , |
---|---|
Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2015
|
Online Access: | http://hdl.handle.net/1721.1/95798 https://orcid.org/0000-0001-6214-4788 https://orcid.org/0000-0002-1293-2097 |