Chemical Genetic Screen for AMPKα2 Substrates Uncovers a Network of Proteins Involved in Mitosis

Chemical Genetic Screen for AMPKα2 Substrates Uncovers a Network of Proteins Involved in Mitosis

The energy-sensing AMP-activated protein kinase (AMPK) is activated by low nutrient levels. Functions of AMPK, other than its role in cellular metabolism, are just beginning to emerge. Here we use a chemical genetics screen to identify direct substrates of AMPK in human cells. We find that AMPK phos...

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Bibliographic Details
Main Authors: Banko, Max R., Allen, Jasmina J., Schaffer, Bethany E., Wilker, Erik W., Tsou, Peiling, White, Jamie L., Villen, Judit, Wang, Beatrice, Kim, Sara R., Sakamoto, Kei, Gygi, Steven P., Cantley, Lewis C., Yaffe, Michael B., Shokat, Kevan M., Brunet, Anne
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/95877
https://orcid.org/0000-0002-9547-3251

Internet

http://hdl.handle.net/1721.1/95877
https://orcid.org/0000-0002-9547-3251

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