Noninvasive optical inhibition with a red-shifted microbial rhodopsin

Noninvasive optical inhibition with a red-shifted microbial rhodopsin

Optogenetic inhibition of the electrical activity of neurons enables the causal assessment of their contributions to brain functions. Red light penetrates deeper into tissue than other visible wavelengths. We present a red-shifted cruxhalorhodopsin, Jaws, derived from Haloarcula (Halobacterium) sali...

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Bibliographic Details
Main Authors: Miri, Mitra L., Busskamp, Volker, Young, Andrew, Ogawa, Masaaki, Ramanlal, Shreshtha B., Forest, Craig R., Chow, Brian Y., Han, Xue, Lin, Yingxi, Roska, Botond, Cardin, Jessica A., Chuong, Amy S., Acker, Leah Christine, Henninger, Michael Alan, Kodandaramaiah, Suhasa Bangalo, Bandler, Rachel C., Allen, Brian Douglas, Boyden, Edward Stuart, Sorensen, Andreas Toft, Klapoetke, Nathan Cao, Matthews, Gillian A., Tye, Kay
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/95967
https://orcid.org/0000-0003-2218-7489
https://orcid.org/0000-0001-6754-0333
https://orcid.org/0000-0002-7002-1275
https://orcid.org/0000-0002-5680-2630
https://orcid.org/0000-0002-5534-6020
https://orcid.org/0000-0001-9969-4281
https://orcid.org/0000-0002-0419-3351

Internet

http://hdl.handle.net/1721.1/95967
https://orcid.org/0000-0003-2218-7489
https://orcid.org/0000-0001-6754-0333
https://orcid.org/0000-0002-7002-1275
https://orcid.org/0000-0002-5680-2630
https://orcid.org/0000-0002-5534-6020
https://orcid.org/0000-0001-9969-4281
https://orcid.org/0000-0002-0419-3351

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