Consequences of Cisplatin Binding on Nucleosome Structure and Dynamics
The effects of cisplatin binding to DNA were explored at the nucleosome level to incorporate key features of the eukaryotic nuclear environment. An X-ray crystal structure of a site-specifically platinated nucleosome carrying a 1,3-cis-{Pt(NH[subscript 3])[subscript 2]}[superscript 2+]-d(GpTpG) intr...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Elsevier
2015
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| Online Access: | http://hdl.handle.net/1721.1/96043 https://orcid.org/0000-0002-2693-4982 |