Caspase-3 Activation via Mitochondria Is Required for Long-Term Depression and AMPA Receptor Internalization

Caspase-3 Activation via Mitochondria Is Required for Long-Term Depression and AMPA Receptor Internalization

NMDA receptor-dependent synaptic modifications, such as long-term potentiation (LTP) and long-term depression (LTD), are essential for brain development and function. LTD occurs mainly by the removal of AMPA receptors from the postsynaptic membrane, but the underlying molecular mechanisms remain unc...

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Bibliographic Details
Main Authors: Li, Zheng, Jo, Jihoon, Jia, Jie-Min, Lo, Shih-Ching, Whitcomb, Daniel J., Jiao, Song, Cho, Kwangwook, Sheng, Morgan
Other Authors: Picower Institute for Learning and Memory
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/96057

Internet

http://hdl.handle.net/1721.1/96057

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