Caspase-3 Activation via Mitochondria Is Required for Long-Term Depression and AMPA Receptor Internalization
NMDA receptor-dependent synaptic modifications, such as long-term potentiation (LTP) and long-term depression (LTD), are essential for brain development and function. LTD occurs mainly by the removal of AMPA receptors from the postsynaptic membrane, but the underlying molecular mechanisms remain unc...
Main Authors: | Li, Zheng, Jo, Jihoon, Jia, Jie-Min, Lo, Shih-Ching, Whitcomb, Daniel J., Jiao, Song, Cho, Kwangwook, Sheng, Morgan |
---|---|
Other Authors: | Picower Institute for Learning and Memory |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2015
|
Online Access: | http://hdl.handle.net/1721.1/96057 |
Similar Items
-
Requirement for AMPA receptor endocytosis and long-term depression in ocular dominance plasticity
by: Smith, Gordon Brawn
Published: (2010) -
Mitochondria are selectively eliminated from eukaryotic cells after blockade of caspases during apoptosis.
by: Xue, L, et al.
Published: (2001) -
Involvement of mitochondria in acetaminophen-induced apoptosis and hepatic injury: roles of cytochrome c, Bax, Bid, and caspases.
by: El-Hassan, H, et al.
Published: (2003) -
Antiproliferation and induction of caspase-8-dependent mitochondria-mediated apoptosis by β-tocotrienol in human lung and brain cancer cell lines
by: Lim, Su Wen, et al.
Published: (2014) -
Phosphorylation of Threonine-19 of PSD-95 by GSK-3β is Required for PSD-95 Mobilization and Long-Term Depression
by: Nelson, Christopher D., et al.
Published: (2014)