Cytosolic Monothiol Glutaredoxins Function in Intracellular Iron Sensing and Trafficking via Their Bound Iron-Sulfur Cluster

Cytosolic Monothiol Glutaredoxins Function in Intracellular Iron Sensing and Trafficking via Their Bound Iron-Sulfur Cluster

Iron is an essential nutrient for cells. It is unknown how iron, after its import into the cytosol, is specifically delivered to iron-dependent processes in various cellular compartments. Here, we identify an essential function of the conserved cytosolic monothiol glutaredoxins Grx3 and Grx4 in intr...

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Bibliographic Details
Main Authors: Mühlenhoff, Ulrich, Molik, Sabine, Godoy, José R., Uzarska, Marta A., Richter, Nadine, Seubert, Andreas, Zhang, Yan, Stubbe, JoAnne, Pierrel, Fabien, Herrero, Enrique, Lillig, Christopher Horst, Lill, Roland
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/96058
https://orcid.org/0000-0001-8076-4489

Internet

http://hdl.handle.net/1721.1/96058
https://orcid.org/0000-0001-8076-4489

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