Structure of the Endonuclease Domain of MutL: Unlicensed to Cut

DNA mismatch repair corrects errors that have escaped polymerase proofreading, increasing replication fidelity 100- to 1000-fold in organisms ranging from bacteria to humans. The MutL protein plays a central role in mismatch repair by coordinating multiple protein-protein interactions that signal st...

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Bibliographic Details
Main Authors: Pillon, Monica C., Lorenowicz, Jessica J., Uckelmann, Michael, Klocko, Andrew D., Mitchell, Ryan R., Chung, Yu Seon, Modrich, Paul, Walker, Graham C., Simmons, Lyle A., Friedhoff, Peter, Guarne, Alba
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier B.V. 2015
Online Access:http://hdl.handle.net/1721.1/96088
https://orcid.org/0000-0001-7243-8261