Structure of the Endonuclease Domain of MutL: Unlicensed to Cut
DNA mismatch repair corrects errors that have escaped polymerase proofreading, increasing replication fidelity 100- to 1000-fold in organisms ranging from bacteria to humans. The MutL protein plays a central role in mismatch repair by coordinating multiple protein-protein interactions that signal st...
Main Authors: | , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Elsevier B.V.
2015
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Online Access: | http://hdl.handle.net/1721.1/96088 https://orcid.org/0000-0001-7243-8261 |