Pharmacological Chaperone Design for Reducing Risk Factor of Parkinson’s Disease from Traditional Chinese Medicine

Dysfunction of β-glucocerebrosidase (GCase) has no hydrolytic activity in patients of Gaucher's disease and increasing the risk factor for Parkinson’s disease occurrence. Pharmacological chaperone design has been used to treat with misfolded protein in related disease, which utilized a small co...

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Bibliographic Details
Main Authors: Huang, Hung-Jin, Lee, Cheng-Chun, Chen, Calvin Yu-Chian
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:http://hdl.handle.net/1721.1/96104