Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

The large serine/threonine protein kinase mTOR regulates cellular and organismal homeostasis by coordinating anabolic and catabolic processes with nutrient, energy, and oxygen availability and growth factor signaling. Cells and organisms experience a wide variety of insults that perturb the homeosta...

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Bibliographic Details
Main Authors: Sengupta, Shomit, Peterson, Timothy Richard, Sabatini, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier B.V. 2015
Online Access:http://hdl.handle.net/1721.1/96111
https://orcid.org/0000-0002-1446-7256