Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress
The large serine/threonine protein kinase mTOR regulates cellular and organismal homeostasis by coordinating anabolic and catabolic processes with nutrient, energy, and oxygen availability and growth factor signaling. Cells and organisms experience a wide variety of insults that perturb the homeosta...
Main Authors: | Sengupta, Shomit, Peterson, Timothy Richard, Sabatini, David |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Elsevier B.V.
2015
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Online Access: | http://hdl.handle.net/1721.1/96111 https://orcid.org/0000-0002-1446-7256 |
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