Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

The Disrupted in Schizophrenia 1 (DISC1) gene is disrupted by a balanced chromosomal translocation (1; 11) (q42; q14.3) in a Scottish family with a high incidence of major depression, schizophrenia, and bipolar disorder. Subsequent studies provided indications that DISC1 plays a role in brain develo...

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Bibliographic Details
Main Authors: Mao, Yingwei, Ge, Xuecai, Frank, Christopher Lee, Madison, Jon M., Koehler, Angela Nicole, Doud, Mary Kathryn, Tassa, Carlos, Berry, Erin M., Soda, Takahiro, Singh, Karun K., Biechele, Travis, Petryshen, Tracey L., Moon, Randall T., Haggarty, Stephen J., Tsai, Li-Huei
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/96175
https://orcid.org/0000-0003-1262-0592