Poly(A)-tail profiling reveals an embryonic switch in translational control

Poly(A)-tail profiling reveals an embryonic switch in translational control

Poly(A) tails enhance the stability and translation of most eukaryotic messenger RNAs, but difficulties in globally measuring poly(A)-tail lengths have impeded greater understanding of poly(A)-tail function. Here we describe poly(A)-tail length profiling by sequencing (PAL-seq) and apply it to measu...

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Bibliographic Details
Main Authors: Subtelny, Alexander Orest, Eichhorn, Stephen William, Chen, Grace, Sive, Hazel L., Bartel, David
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/96227
https://orcid.org/0000-0002-6410-4699
https://orcid.org/0000-0002-3872-2856
https://orcid.org/0000-0002-4890-424X
https://orcid.org/0000-0001-5029-5909
https://orcid.org/0000-0001-9051-1696

Internet

http://hdl.handle.net/1721.1/96227
https://orcid.org/0000-0002-6410-4699
https://orcid.org/0000-0002-3872-2856
https://orcid.org/0000-0002-4890-424X
https://orcid.org/0000-0001-5029-5909
https://orcid.org/0000-0001-9051-1696

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