Poly(A)-tail profiling reveals an embryonic switch in translational control
Poly(A) tails enhance the stability and translation of most eukaryotic messenger RNAs, but difficulties in globally measuring poly(A)-tail lengths have impeded greater understanding of poly(A)-tail function. Here we describe poly(A)-tail length profiling by sequencing (PAL-seq) and apply it to measu...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Nature Publishing Group
2015
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| Online Access: | http://hdl.handle.net/1721.1/96227 https://orcid.org/0000-0002-6410-4699 https://orcid.org/0000-0002-3872-2856 https://orcid.org/0000-0002-4890-424X https://orcid.org/0000-0001-5029-5909 https://orcid.org/0000-0001-9051-1696 |