Impaired cholecystokinin-induced gallbladder emptying incriminated in spontaneous “black” pigment gallstone formation in germfree Swiss Webster mice

Impaired cholecystokinin-induced gallbladder emptying incriminated in spontaneous “black” pigment gallstone formation in germfree Swiss Webster mice

“Black” pigment gallstones form in sterile gallbladder bile in the presence of excess bilirubin conjugates (“hyperbilirubinbilia”) from ineffective erythropoiesis, hemolysis, or induced enterohepatic cycling (EHC) of unconjugated bilirubin. Impaired gallbladder motility is a less well-studied risk f...

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Bibliographic Details
Main Authors: Woods, Stephanie E., Leonard, Monika R., Hayden, Joshua A., Brophy, Megan Brunjes, Bernert, Kara R., Lavoie, Brigitte, Muthupalani, Sureshkumar, Whary, Mark T., Mawe, Gary M., Nolan, Elizabeth M., Carey, Martin C., Fox, James G.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Physiological Society 2015
Online Access:http://hdl.handle.net/1721.1/96251
https://orcid.org/0000-0002-6153-8803
https://orcid.org/0000-0001-9307-6116

Internet

http://hdl.handle.net/1721.1/96251
https://orcid.org/0000-0002-6153-8803
https://orcid.org/0000-0001-9307-6116

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