SR Proteins Collaborate with 7SK and Promoter-Associated Nascent RNA to Release Paused Polymerase

SR Proteins Collaborate with 7SK and Promoter-Associated Nascent RNA to Release Paused Polymerase

RNAP II is frequently paused near gene promoters in mammals, and its transition to productive elongation requires active recruitment of P-TEFb, a cyclin-dependent kinase for RNAP II and other key transcription elongation factors. A fraction of P-TEFb is sequestered in an inhibitory complex containin...

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Bibliographic Details
Main Authors: Ji, Xiong, Zhou, Yu, Pandit, Shatakshi, Huang, Jie, Li, Hairi, Lin, Charles Y., Xiao, Rui, Fu, Xiang-Dong, Burge, Christopher B
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/96261

Internet

http://hdl.handle.net/1721.1/96261

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