Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

Screens for agents that specifically kill epithelial cancer stem cells (CSCs) have not been possible due to the rarity of these cells within tumor cell populations and their relative instability in culture. We describe here an approach to screening for agents with epithelial CSC-specific toxicity. W...

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Bibliographic Details
Main Authors: Jiang, Guozhi, Tao, Kai, Kuperwasser, Charlotte, Gupta, Piyush, Onder, Tamer T, Weinberg, Robert A, Lander, Eric Steven
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/96273
https://orcid.org/0000-0002-0895-3557
https://orcid.org/0000-0002-9703-1780