Direct Lineage Conversion of Adult Mouse Liver Cells and B Lymphocytes to Neural Stem Cells

Direct Lineage Conversion of Adult Mouse Liver Cells and B Lymphocytes to Neural Stem Cells

Overexpression of transcription factors has been used to directly reprogram somatic cells into a range of other differentiated cell types, including multipotent neural stem cells (NSCs), that can be used to generate neurons and glia. However, the ability to maintain the NSC state independent of the...

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Bibliographic Details
Main Authors: Cassady, John P., D’Alessio, Ana C., Sarkar, Sovan, Fan, Zi Peng, Ganz, Kibibi, Roessler, Reinhard, Sur, Mriganka, Young, Richard A., Jaenisch, Rudolf, Dani, Vardhan, Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/96277
https://orcid.org/0000-0001-5478-1568
https://orcid.org/0000-0003-2442-5671
https://orcid.org/0000-0001-8855-8647

Internet

http://hdl.handle.net/1721.1/96277
https://orcid.org/0000-0001-5478-1568
https://orcid.org/0000-0003-2442-5671
https://orcid.org/0000-0001-8855-8647

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