Direct Lineage Conversion of Adult Mouse Liver Cells and B Lymphocytes to Neural Stem Cells
Overexpression of transcription factors has been used to directly reprogram somatic cells into a range of other differentiated cell types, including multipotent neural stem cells (NSCs), that can be used to generate neurons and glia. However, the ability to maintain the NSC state independent of the...
Main Authors: | Cassady, John P., D’Alessio, Ana C., Sarkar, Sovan, Fan, Zi Peng, Ganz, Kibibi, Roessler, Reinhard, Sur, Mriganka, Young, Richard A., Jaenisch, Rudolf, Dani, Vardhan, Young, Richard A. |
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Other Authors: | Massachusetts Institute of Technology. Computational and Systems Biology Program |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2015
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Online Access: | http://hdl.handle.net/1721.1/96277 https://orcid.org/0000-0001-5478-1568 https://orcid.org/0000-0003-2442-5671 https://orcid.org/0000-0001-8855-8647 |
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