Family-wide analysis of poly(ADP-ribose) polymerase activity

The poly(adenosine diphosphate (ADP)-ribose) polymerase (PARP) protein family generates ​ADP-ribose (​ADPr) modifications onto target proteins using ​NAD[superscript +] as substrate. Based on the composition of three ​NAD[superscript +] coordinating amino acids, the H-Y-E motif, each PARP is predict...

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Bibliographic Details
Main Authors: Vyas, Sejal, Matic, Ivan, Uchima, Lilen, Rood, Jenny, Zaja, Roko, Hay, Ronald T., Ahel, Ivan, Chang, Paul
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/96282
https://orcid.org/0000-0001-5253-8185