Isodicentric Y Chromosomes and Sex Disorders as Byproducts of Homologous Recombination that Maintains Palindromes

Isodicentric Y Chromosomes and Sex Disorders as Byproducts of Homologous Recombination that Maintains Palindromes

Massive palindromes in the human Y chromosome harbor mirror-image gene pairs essential for spermatogenesis. During evolution, these gene pairs have been maintained by intrapalindrome, arm-to-arm recombination. The mechanism of intrapalindrome recombination and risk of harmful effects are unknown. We...

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Bibliographic Details
Main Authors: Lange, Julian, Skaletsky, Helen, van Daalen, Saskia K.M., Embry, Stephanie L., Korver, Cindy M., Brown, Laura G., Oates, Robert D., Silber, Sherman, Repping, Sjoerd, Page, David C
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/96285
https://orcid.org/0000-0001-9920-3411

Internet

http://hdl.handle.net/1721.1/96285
https://orcid.org/0000-0001-9920-3411

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