Isodicentric Y Chromosomes and Sex Disorders as Byproducts of Homologous Recombination that Maintains Palindromes
Massive palindromes in the human Y chromosome harbor mirror-image gene pairs essential for spermatogenesis. During evolution, these gene pairs have been maintained by intrapalindrome, arm-to-arm recombination. The mechanism of intrapalindrome recombination and risk of harmful effects are unknown. We...
Główni autorzy: | Lange, Julian, Skaletsky, Helen, van Daalen, Saskia K.M., Embry, Stephanie L., Korver, Cindy M., Brown, Laura G., Oates, Robert D., Silber, Sherman, Repping, Sjoerd, Page, David C |
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Kolejni autorzy: | Massachusetts Institute of Technology. Department of Biology |
Format: | Artykuł |
Język: | en_US |
Wydane: |
Elsevier
2015
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Dostęp online: | http://hdl.handle.net/1721.1/96285 https://orcid.org/0000-0001-9920-3411 |
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