Context-Dependent Transformation of Adult Pancreatic Cells by Oncogenic K-Ras
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal human malignancies. To investigate the cellular origin(s) of this cancer, we determined the effect of PDAC-relevant gene mutations in distinct cell types of the adult pancreas. We show that a subpopulation of Pdx1-expressing cells is...
| Main Authors: | , , , , , , , , |
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| 其他作者: | |
| 格式: | 文件 |
| 语言: | en_US |
| 出版: |
Elsevier B.V.
2015
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| 在线阅读: | http://hdl.handle.net/1721.1/96295 https://orcid.org/0000-0001-5785-8911 |