Single cell sequencing reveals low levels of aneuploidy across mammalian tissues
Whole-chromosome copy number alterations, also known as aneuploidy, are associated with adverse consequences in most cells and organisms. However, high frequencies of aneuploidy have been reported to occur naturally in the mammalian liver and brain, fueling speculation that aneuploidy provides a sel...
Main Authors: | Wu, Jie, Whittaker, Charles A., Knouse, Kristin Ann, Amon, Angelika B |
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Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2015
|
Online Access: | http://hdl.handle.net/1721.1/96316 https://orcid.org/0000-0002-0989-8115 https://orcid.org/0000-0001-9837-0314 https://orcid.org/0000-0003-0649-7428 |
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