The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

Reprogramming of fibroblasts to induced pluripotent stem cells (iPSCs) entails a mesenchymal to epithelial transition (MET). While attempting to dissect the mechanism of MET during reprogramming, we observed that knockdown (KD) of the epithelial-to-mesenchymal transition (EMT) factor SNAI1 (SNAIL) p...

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Bibliographic Details
Main Authors: Unternaehrer, Juli J., Zhao, Rui, Kim, Kitai, Cesana, Marcella, Powers, John T., Ratanasirintrawoot, Sutheera, Onder, Tamer T., Shibue, Tsukasa, Weinberg, Robert A., Daley, George Q., Weinberg, Robert A
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/96337
https://orcid.org/0000-0002-0895-3557

Internet

http://hdl.handle.net/1721.1/96337
https://orcid.org/0000-0002-0895-3557

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