Dynamic myosin phosphorylation regulates contractile pulses and tissue integrity during epithelial morphogenesis

Apical constriction is a cell shape change that promotes epithelial bending. Activation of nonmuscle myosin II (Myo-II) by kinases such as Rho-associated kinase (Rok) is important to generate contractile force during apical constriction. Cycles of Myo-II assembly and disassembly, or pulses, are asso...

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Bibliographic Details
Main Authors: Tworoger, Michael B., Vasquez, Claudia G, Martin, Adam C
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Rockefeller University Press 2015
Online Access:http://hdl.handle.net/1721.1/96347
https://orcid.org/0000-0002-8987-7508
https://orcid.org/0000-0001-8060-2607