A Candida albicans CRISPR system permits genetic engineering of essential genes and gene families

Candida albicans is a pathogenic yeast that causes mucosal and systematic infections with high mortality. The absence of facile molecular genetics has been a major impediment to analysis of pathogenesis. The lack of meiosis coupled with the absence of plasmids makes genetic engineering cumbersome, e...

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Bibliographic Details
Main Authors: Vyas, Valmik K., Barrasa, M. Inmaculada, Fink, Gerald R
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2015
Online Access:http://hdl.handle.net/1721.1/96395
https://orcid.org/0000-0003-3704-2899