A Candida albicans CRISPR system permits genetic engineering of essential genes and gene families
Candida albicans is a pathogenic yeast that causes mucosal and systematic infections with high mortality. The absence of facile molecular genetics has been a major impediment to analysis of pathogenesis. The lack of meiosis coupled with the absence of plasmids makes genetic engineering cumbersome, e...
Main Authors: | Vyas, Valmik K., Barrasa, M. Inmaculada, Fink, Gerald R |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
American Association for the Advancement of Science (AAAS)
2015
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Online Access: | http://hdl.handle.net/1721.1/96395 https://orcid.org/0000-0003-3704-2899 |
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