Coherent two-dimensional infrared spectroscopy: Quantitative analysis of protein secondary structure in solution

We present a method to quantitatively determine the secondary structure composition of globular proteins using coherent two-dimensional infrared (2DIR) spectroscopy of backbone amide I vibrations (1550–1720 cm−1). Sixteen proteins with known crystal structures were used to construct a library of 2DI...

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Bibliographic Details
Main Authors: Tokmakoff, Andrei, Jones, Kevin C., Reppert, Mike E., Peng, Chunte Sam, Baiz, Carlos R.
Format: Dataset
Published: Royal Society of Chemistry 2015
Subjects:
Online Access:http://hdl.handle.net/1721.1/77962
http://hdl.handle.net/1721.1/96430