Next-generation sequencing reveals the biological significance of the N[superscript 2],3-ethenoguanine lesion in vivo

Next-generation sequencing reveals the biological significance of the N[superscript 2],3-ethenoguanine lesion in vivo

Etheno DNA adducts are a prevalent type of DNA damage caused by vinyl chloride (VC) exposure and oxidative stress. Etheno adducts are mutagenic and may contribute to the initiation of several pathologies; thus, elucidating the pathways by which they induce cellular transformation is critical. Althou...

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Bibliographic Details
Main Authors: Chang, Shiou-chi, Wu, Jie, Delaney, James C., Li, Deyu, Zhao, Linlin, Christov, Plamen P., Yau, Emily, Singh, Vipender, Jost, Marco, Marnett, Lawrence J., Rizzo, Carmelo J., Levine, Stuart S., Guengerich, F. Peter, Essigmann, John M., Drennan, Catherine L, Fedeles, Bogdan I
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: Oxford University Press 2015
Online Access:http://hdl.handle.net/1721.1/96431
https://orcid.org/0000-0002-0989-8115
https://orcid.org/0000-0001-5486-2755
https://orcid.org/0000-0001-6159-0778
https://orcid.org/0000-0002-8241-4834
https://orcid.org/0000-0002-2196-5691
https://orcid.org/0000-0002-2494-7763

Internet

http://hdl.handle.net/1721.1/96431
https://orcid.org/0000-0002-0989-8115
https://orcid.org/0000-0001-5486-2755
https://orcid.org/0000-0001-6159-0778
https://orcid.org/0000-0002-8241-4834
https://orcid.org/0000-0002-2196-5691
https://orcid.org/0000-0002-2494-7763

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