Next-generation sequencing reveals the biological significance of the N[superscript 2],3-ethenoguanine lesion in vivo

Next-generation sequencing reveals the biological significance of the N[superscript 2],3-ethenoguanine lesion in vivo

Etheno DNA adducts are a prevalent type of DNA damage caused by vinyl chloride (VC) exposure and oxidative stress. Etheno adducts are mutagenic and may contribute to the initiation of several pathologies; thus, elucidating the pathways by which they induce cellular transformation is critical. Althou...

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Bibliographic Details
Main Authors:	Chang, Shiou-chi, Wu, Jie, Delaney, James C., Li, Deyu, Zhao, Linlin, Christov, Plamen P., Yau, Emily, Singh, Vipender, Jost, Marco, Marnett, Lawrence J., Rizzo, Carmelo J., Levine, Stuart S., Guengerich, F. Peter, Essigmann, John M., Drennan, Catherine L, Fedeles, Bogdan I
Other Authors:	Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format:	Article
Language:	en_US
Published:	Oxford University Press 2015
Online Access:	http://hdl.handle.net/1721.1/96431 https://orcid.org/0000-0002-0989-8115 https://orcid.org/0000-0001-5486-2755 https://orcid.org/0000-0001-6159-0778 https://orcid.org/0000-0002-8241-4834 https://orcid.org/0000-0002-2196-5691 https://orcid.org/0000-0002-2494-7763

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