Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney

Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney

Inflammation is accompanied by the release of highly reactive oxygen and nitrogen species (RONS) that damage DNA, among other cellular molecules. Base excision repair (BER) is initiated by DNA glycosylases and is crucial in repairing RONS-induced DNA damage; the alkyladenine DNA glycosylase (Aag/Mpg...

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Bibliographic Details
Main Authors: Daneshmand, Ali, Mazumder, Aprotim, Allocca, Mariacarmela, Calvo, Jennifer A., Abolhassani, Nona, Jhun, Iny, Muthupalani, Sureshkumar, Ayata, Cenk, Ebrahimkhani, Mohammad Reza, Samson, Leona D
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2015
Online Access:http://hdl.handle.net/1721.1/96476
https://orcid.org/0000-0002-7112-1454

Internet

http://hdl.handle.net/1721.1/96476
https://orcid.org/0000-0002-7112-1454

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