Tailoring Chimeric Ligands for Studying and Biasing ErbB Receptor Family Interactions

Tailoring Chimeric Ligands for Studying and Biasing ErbB Receptor Family Interactions

Described is the development and application of a versatile semisynthetic strategy, based on a combination of sortase-mediated coupling and tetrazine ligation chemistry, which can be exploited for the efficient incorporation of tunable functionality into chimeric recombinant proteins. To demonstrate...

Full description

Bibliographic Details
Main Authors: Krueger, Andrew T., Kroll, Carsten, Sanchez, Edgar, Imperiali, Barbara, Griffith, Linda G
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Wiley Blackwell 2015
Online Access:http://hdl.handle.net/1721.1/96496
https://orcid.org/0000-0002-5749-7869
https://orcid.org/0000-0002-1801-5548

Internet

http://hdl.handle.net/1721.1/96496
https://orcid.org/0000-0002-5749-7869
https://orcid.org/0000-0002-1801-5548

Similar Items