Mapping the Cellular Response to Small Molecules Using Chemogenomic Fitness Signatures
Genome-wide characterization of the in vivo cellular response to perturbation is fundamental to understanding how cells survive stress. Identifying the proteins and pathways perturbed by small molecules affects biology and medicine by revealing the mechanisms of drug action. We used a yeast chemogen...
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| Formato: | Artigo |
| Idioma: | en_US |
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American Association for the Advancement of Science (AAAS)
2015
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| Acesso em linha: | http://hdl.handle.net/1721.1/96521 https://orcid.org/0000-0002-1505-0479 |