Redox signaling via the molecular chaperone BiP protects cells against endoplasmic reticulum-derived oxidative stress
Oxidative protein folding in the endoplasmic reticulum (ER) has emerged as a potentially significant source of cellular reactive oxygen species (ROS). Recent studies suggest that levels of ROS generated as a byproduct of oxidative folding rival those produced by mitochondrial respiration. Mechanisms...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
eLife Sciences Publications, Ltd.
2015
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| Online Access: | http://hdl.handle.net/1721.1/96523 https://orcid.org/0000-0002-1505-0479 |