Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance

Macroautophagy (autophagy hereafter) recycles intracellular components to sustain mitochondrial metabolism that promotes the growth, stress tolerance, and malignancy of lung cancers, suggesting that autophagy inhibition may have antitumor activity. To assess the functional significance of autophagy...

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Bibliographic Details
Main Authors: Karsli-Uzunbas, Gizem, Guo, Jessie Yanxiang, Price, Sandy, Teng, Xin, Laddha, Saurabh V., Khor, Sinan, Kalaany, Nada Y., Chan, Chang S., Rabinowitz, Joshua D., White, Eileen, Jacks, Tyler E
Other Authors: MIT Kavli Institute for Astrophysics and Space Research
Format: Article
Language:en_US
Published: American Association for Cancer Research 2015
Online Access:http://hdl.handle.net/1721.1/96526
https://orcid.org/0000-0001-5785-8911