Discovery and saturation analysis of cancer genes across 21 tumour types

Discovery and saturation analysis of cancer genes across 21 tumour types

Although a few cancer genes are mutated in a high proportion of tumours of a given type (>20%), most are mutated at intermediate frequencies (2–20%). To explore the feasibility of creating a comprehensive catalogue of cancer genes, we analysed somatic point mutations in exome sequences from 4,742...

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Detalhes bibliográficos
Main Authors: Lawrence, Michael S., Stojanov, Petar, Mermel, Craig H., Robinson, James T., Garraway, Levi A., Golub, Todd R., Meyerson, Matthew L., Gabriel, Stacey B., Getz, Gad, Lander, Eric Steven
Outros Autores: Massachusetts Institute of Technology. Department of Biology
Formato: Artigo
Idioma:en_US
Publicado em: Nature Publishing Group 2015
Acesso em linha:http://hdl.handle.net/1721.1/96680

Internet

http://hdl.handle.net/1721.1/96680

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