DNA Copy-Number Control through Inhibition of Replication Fork Progression

Proper control of DNA replication is essential to ensure faithful transmission of genetic material and prevent chromosomal aberrations that can drive cancer progression and developmental disorders. DNA replication is regulated primarily at the level of initiation and is under strict cell-cycle regul...

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Bibliographic Details
Main Authors: Nordman, Jared T., Kozhevnikova, Elena N., Verrijzer, C. Peter, Pindyurin, Alexey V., Andreyeva, Evgeniya N., Shloma, Victor V., Zhimulev, Igor F., Orr-Weaver, Terry
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/96688
https://orcid.org/0000-0002-7934-111X