Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition

Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition

Characterizing changes in protein-protein interactions associated with sequence variants (e.g., disease-associated mutations or splice forms) or following exposure to drugs, growth factors or hormones is critical to understanding how protein complexes are built, localized and regulated. Affinity pur...

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Bibliographic Details
Main Authors: Lambert, Jean-Philippe, Ivosev, Gordana, Couzens, Amber L, Larsen, Brett, Taipale, Mikko, Lin, Zhen-Yuan, Zhong, Quan, Lindquist, Susan, Vidal, Marc, Aebersold, Ruedi, Pawson, Tony, Bonner, Ron, Tate, Stephen, Gingras, Anne-Claude
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/96689
https://orcid.org/0000-0003-1307-882X

Internet

http://hdl.handle.net/1721.1/96689
https://orcid.org/0000-0003-1307-882X

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