Trade-offs between tRNA abundance and mRNA secondary structure support smoothing of translation elongation rate

Trade-offs between tRNA abundance and mRNA secondary structure support smoothing of translation elongation rate

Translation of protein from mRNA is a complex multi-step process that occurs at a non-uniform rate. Variability in ribosome speed along an mRNA enables refinement of the proteome and plays a critical role in protein biogenesis. Detailed single protein studies have found both tRNA abundance and mRNA...

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Bibliographic Details
Main Authors: Roubos, J. A., Gorochowski, Thomas, Ignatova, Zoya, Bovenberg, Roel A. L., Roubos, Johannes A.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Oxford University Press 2015
Online Access:http://hdl.handle.net/1721.1/96717
https://orcid.org/0000-0003-1702-786X

Internet

http://hdl.handle.net/1721.1/96717
https://orcid.org/0000-0003-1702-786X

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