SPASM and Twitch Domains in S-Adenosylmethionine (SAM) Radical Enzymes
S-Adenosylmethionine (SAM, also known as AdoMet) radical enzymes use SAM and a [4Fe-4S] cluster to catalyze a diverse array of reactions. They adopt a partial triose-phosphate isomerase (TIM) barrel fold with N- and C-terminal extensions that tailor the structure of the enzyme to its specific functi...
Main Authors: | , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
American Society for Biochemistry and Molecular Biology (ASBMB)
2015
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Online Access: | http://hdl.handle.net/1721.1/96728 https://orcid.org/0000-0001-5486-2755 https://orcid.org/0000-0001-8578-7559 |