SPASM and Twitch Domains in S-Adenosylmethionine (SAM) Radical Enzymes

S-Adenosylmethionine (SAM, also known as AdoMet) radical enzymes use SAM and a [4Fe-4S] cluster to catalyze a diverse array of reactions. They adopt a partial triose-phosphate isomerase (TIM) barrel fold with N- and C-terminal extensions that tailor the structure of the enzyme to its specific functi...

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Bibliographic Details
Main Authors: Goldman, Peter J., Grell, Tsehai Ariane, Drennan, Catherine L
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Society for Biochemistry and Molecular Biology (ASBMB) 2015
Online Access:http://hdl.handle.net/1721.1/96728
https://orcid.org/0000-0001-5486-2755
https://orcid.org/0000-0001-8578-7559