DNA methylation dynamics of the human preimplantation embryo

DNA methylation dynamics of the human preimplantation embryo

In mammals, cytosine methylation is predominantly restricted to CpG dinucleotides and stably distributed across the genome, with local, cell-type-specific regulation directed by DNA binding factors. This comparatively static landscape is in marked contrast with the events of fertilization, during wh...

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Bibliographic Details
Main Authors: Smith, Zachary D., Chan, Michelle Mei Wah, Humm, Kathryn C., Karnik, Rahul, Mekhoubad, Shila, Regev, Aviv, Eggan, Kevin, Meissner, Alexander
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/96731
https://orcid.org/0000-0001-8567-2049

Internet

http://hdl.handle.net/1721.1/96731
https://orcid.org/0000-0001-8567-2049

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