Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive
Rapamycin, an inhibitor of the mechanistic target of rapamycin (mTOR) signaling pathway, extends the life span of yeast, worms, flies, and mice. Interventions that promote longevity are often correlated with increased insulin sensitivity, and it therefore is surprising that chronic rapamycin treatme...
Main Authors: | , , , , , |
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Format: | Article |
Language: | en_US |
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Wiley Blackwell
2015
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Online Access: | http://hdl.handle.net/1721.1/96741 https://orcid.org/0000-0002-0079-4467 https://orcid.org/0000-0002-1446-7256 |