Licensing of Primordial Germ Cells for Gametogenesis Depends on Genital Ridge Signaling

Licensing of Primordial Germ Cells for Gametogenesis Depends on Genital Ridge Signaling

In mouse embryos at mid-gestation, primordial germ cells (PGCs) undergo licensing to become gametogenesis-competent cells (GCCs), gaining the capacity for meiotic initiation and sexual differentiation. GCCs then initiate either oogenesis or spermatogenesis in response to gonadal cues. Germ cell lice...

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Bibliographic Details
Main Authors: Hu, Yueh-Chiang, Nicholls, Peter K., Soh, Ying Qi Shirleen, Daniele, Joseph R., Junker, Jan Philipp, van Oudenaarden, Alexander, Page, David C
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Public Library of Science 2015
Online Access:http://hdl.handle.net/1721.1/96744
https://orcid.org/0000-0001-9920-3411

Internet

http://hdl.handle.net/1721.1/96744
https://orcid.org/0000-0001-9920-3411

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