Licensing of Primordial Germ Cells for Gametogenesis Depends on Genital Ridge Signaling
In mouse embryos at mid-gestation, primordial germ cells (PGCs) undergo licensing to become gametogenesis-competent cells (GCCs), gaining the capacity for meiotic initiation and sexual differentiation. GCCs then initiate either oogenesis or spermatogenesis in response to gonadal cues. Germ cell lice...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Public Library of Science
2015
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| Online Access: | http://hdl.handle.net/1721.1/96744 https://orcid.org/0000-0001-9920-3411 |